Intravenous sugar solution

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An intravenous sugar solution is a solution with a sugar (usually glucose, as known as dextrose, with water as the solvent) used for intravenous therapy, where it may function both as a means of maintaining tissue hydration and a means of parenteral nutrition. Most IV sugar solutions are crystalloid solutions.

Types

Types of glucose/dextrose include:

  • D5W (5% dextrose in water), which consists of 278 mmol/L dextrose
  • D5NS (5% dextrose in normal saline), which, in addition, contains normal saline (0.90% w/v of NaCl).
    • D5 1/2NS 5% dextrose in half amount of normal saline (0.45% w/v of NaCl).[1]
  • D5LR (5% dextrose in lactated Ringer solution)

The percentage is a mass percentage, so a 5% glucose/dextrose solution contains 50 g/L of glucose/dextrose (Quite simply, 5% dextrose means the solution contains 5g/100ml of solution).

Glucose provides energy 4 kcal/gram, so a 5% glucose solution provides 0.2 kcal/ml. If prepared from dextrose monohydrate, which provides 3.4 kcal/gram, a 5% solution provides 0.17 kcal/ml.[2]

Indications

Administering a 5% sugar solution peri- and postoperatively usually achieves a good balance between starvation reactions and hyperglycemia caused by sympathetic activation. A 10% solution may be more appropriate when the stress response from the reaction has decreased, after approximately one day after surgery. After more than approximately 2 days, a more complete regimen of total parenteral nutrition is indicated.

In patients with hypernatremia and euvolemia, free water can be replaced using either 5% D/W or 0.45% saline.

In patients with fatty-acid oxidation disorders (FOD), 10% solution may be appropriate upon arrival to the emergency room.

Dangers

Intravenous glucose is used in some Asian countries as a pick-me-up, for "energy," but is not a part of routine medical care in the United States where a glucose solution is a prescription drug. Asian immigrants to the United States are at risk if they seek intravenous glucose treatment. It may be had at store-front clinics catering to Asian immigrants, but, despite having no more effect than drinking sugared water, poses medical risks such as the possibility of infection. It is commonly called "ringer."[3]

See also

References

  1. eMedicine > Hypernatremia: Treatment & Medication By Ivo Lukitsch and Trung Q Pham. Updated: Apr 19, 2010
  2. Calculating Parenteral Feedings D. Chen-Maynard at California State University, San Bernardino. Retrieved September 2010. HSCI 368
  3. Lua error in package.lua at line 80: module 'strict' not found.