Lanthanum carbonate

Lanthanum carbonate

Names
IUPAC name Lanthanum carbonate
Identifiers
CAS Number	54451-24-0 Y
ChEMBL	ChEMBL2096647 N
ChemSpider	147758 Y
Jmol 3D model	Interactive image
PubChem	168924
InChI InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 Y Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H Y InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 Key: NZPIUJUFIFZSPW-CYFPFDDLAT
SMILES [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O
Properties
Chemical formula	La2(CO3)3
Molar mass	457.838 g/mol
Appearance	White powder, hygroscopic
Density	2.6–2.7 g/cm3
Melting point	decomposes
Solubility in water	negligible
Solubility	soluble in acids
Pharmacology
ATC code	V03AE03
Vapor pressure	{{{value}}}
Related compounds
Other anions	Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Lanthanum carbonate, La₂(CO₃)₃, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal, along with monazite.

Chemistry

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

• for production of lanthanum strontium manganite, primarily for solid oxide fuel cell applications;
• for production of certain high-temperature superconductors, such as La_2-xSr_xCuO₂.

Human and veterinary medicine

Lanthanum carbonate is used in medicine as a phosphate binder. As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000mg tablet is 2.2cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats suffering from hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.

Other applications

Lanthanum carbonate is also used for the tinting of glass, for water treatment, and as a catalyst for hydrocarbon cracking.

External links

• Lanthanum - medlineplus.org
• Fosrenol.com - the manufacturer's web site
• Fosrenol - Drugs.com
• Fosrenol - Medscape.com
• PhosphorusControl.com - PhosphorusControl.com
• Bayer Animal Health