File:DFMO mechanism.png

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Summary

Reaction mechanism for the inhibition of ornithine decarboxylase by the suicide inhibitor difluromethylornithine (DFMO or Eflornithine) Poulin R, Lu L, Ackermann B, Bey P, Pegg AE. <a rel="nofollow" class="external text" href="http://www.jbc.org/cgi/reprint/267/1/150">Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites.</a> J Biol Chem. 1992 Jan 5;267(1):150–8. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/1730582?dopt=Abstract">PMID 1730582</a>

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current16:21, 7 January 2017Thumbnail for version as of 16:21, 7 January 2017980 × 400 (13 KB)127.0.0.1 (talk)Reaction mechanism for the inhibition of ornithine decarboxylase by the suicide inhibitor difluromethylornithine (DFMO or Eflornithine) Poulin R, Lu L, Ackermann B, Bey P, Pegg AE. <a rel="nofollow" class="external text" href="http://www.jbc.org/cgi/reprint/267/1/150"><i>Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites.</i></a> J Biol Chem. 1992 Jan 5;267(1):150–8. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/1730582?dopt=Abstract">PMID 1730582</a>
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