CEP135

Centrosomal protein 135kDa
Identifiers
Symbols	CEP135 ; CEP4; KIAA0635; MCPH8
External IDs	OMIM: 611423 MGI: 2681869 HomoloGene: 45709 GeneCards: CEP135 Gene
Gene ontology Molecular function • protein binding • protein C-terminus binding Cellular component • centrosome • centriole • cytosol Biological process • G2/M transition of mitotic cell cycle • mitotic cell cycle • organelle organization • centriole replication • centriole-centriole cohesion Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE CEP135 206003 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9662	381644
Ensembl	ENSG00000174799	ENSMUSG00000036403
UniProt	Q66GS9	Q6P5D4
RefSeq (mRNA)	NM_014645	NM_199032
RefSeq (protein)	NP_079285	NP_950197
Location (UCSC)	Chr 4: 55.95 – 56.03 Mb	Chr 5: 76.59 – 76.65 Mb
PubMed search	[1]	[2]

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene. It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material. CEP135 is required for the centriolar localization of CEP250.