4-Hydroxyphenylacetic acid

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4-Hydroxyphenylacetic acid
Chemical structure of 4-hydroxyphenylacetic acid
Names
IUPAC name
2-(4-Hydroxyphenyl)acetic acid
Other names
p-Hydroxyphenylacetic acid
Identifiers
156-38-7 YesY
1448766
ChEBI CHEBI:18101 YesY
ChEMBL ChEMBL1772 YesY
ChemSpider 124 YesY
EC Number 205-851-3
Jmol 3D model Interactive image
PubChem 127
  • InChI=1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11) YesY
    Key: XQXPVVBIMDBYFF-UHFFFAOYSA-N YesY
  • O=C(O)Cc1ccc(O)cc1
Properties
C8H8O3
Molar mass 152.15 g·mol−1
Appearance Beige powder
Melting point 150 °C (302 °F; 423 K)
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

4-Hydroxyphenylacetic acid is a chemical compound found in olive oil[1] and beer.[2] In industry the chemical is an intermediate used to synthesize atenolol[3] and 3,4-dihydroxyphenylacetic acid.[4]

Synthesis

4-Hydroxyphenylacetic acid is obtained by reducing 4-hydroxymandelic acid with elemental phosphorus and iodine.[3]

References

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  2. Determination of free and bound phenolic acids in beer. M. Nardini and A. Ghiselli, Food Chemistry, January 2004, Volume 84, Issue 1, Pages 137–143, doi:10.1016/S0308-8146(03)00257-7
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