3-(p-Fluorobenzoyloxy)tropane
Systematic (IUPAC) name | |
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(1R,5S)-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-4-fluorobenzoate
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Clinical data | |
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Routes of administration |
insufflated |
Identifiers | |
CAS Number | 172883-97-5 |
PubChem | CID: 5147770 |
ChemSpider | 4321292 |
Chemical data | |
Formula | C15H18FNO2 |
Molecular mass | 263.307 g/mol |
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3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-Pseudotropyl-4-fluorobenzoate, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic.[citation needed] It has been investigated as a potential radiolabelled agent for studying receptor binding,[1] but was not adopted for this application. The main application for fluorotropacocaine however has been as a designer drug analogue of cocaine, first detected by the EMCDDA in 2008,[2][3] and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such as caffeine, dimethocaine, desoxypipradrol or substituted cathinone derivatives.[4][5]
See also
References
- ↑ Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN 0-306-44035-0
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Kavanagh P, Angelov D, O'Brien J, Fox J, O'Donnell C, Christie R, Power JD, McDermott SD. The syntheses and characterization 3β-(4-fluorobenzoyloxy)tropane (fluorotropacocaine) and its 3α isomer. Drug Testing and Analysis. 2011 Nov 18. doi:10.1002/dta.362 PMID 22102564
- ↑ An overview of new psychoactive substances and the outlets supplying them
- ↑ Reitzel LA, Dalsgaard PW, Müller IB, Cornett C. Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish Internet company. Drug Testing and Analysis. 2011 Nov 18. doi:10.1002/dta.358 PMID 22102551
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- Tropanes
- Dopamine reuptake inhibitors
- Stimulants
- Local anesthetics
- Fluoroarenes
- Benzoates